Secretagogues stimulate GH release via ghrelin or GHRH receptors
Several factors cause this age-related NAD+ decline: NAD+-consuming enzymes like CD38 and PARPs become more active NAMPT, the key enzyme in NAD+ production, decreases Long-term inflammation and oxidative stress activate PARP1 More senescent cells appear and deplete NAD+ through inflammatory signals The effects of falling NAD+ levels run deepcells don't deal very well with energy production and repair mechanisms when NAD+ is low
It also powers glutathione Stransferase (the enzyme family that tags toxins so the liver can excrete them) and helps immune cells function by maintaining redox balance, the cells internal electron flow
Wrist Circles: Slowly rotate wrist in circles, 10 each direction, 3 times daily Forearm Stretch: Extend arm, gently pull fingers back, hold 30 seconds Ball Squeeze (light): Gentle squeezes with soft stress ball, 10 reps, 2 times daily Supination/Pronation: Rotate forearm palm-up to palm-down, 15 reps Progressive Loading Phase (Weeks 3-6) As pain decreases and function improves, gradually introduce more challenging exercises
