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Small-molecule probes, such as TSQ and Zinquin, pioneered live-cell imaging in the 1990s, although early designs were limited by poor selectivity and lack of organelle specificity 185,186

Neurobehavioral dysfunction in a mouse model of Down syndrome: upregulation of cystathionine -synthase, H2S overproduction, altered protein persulfidation, synaptic dysfunction, endoplasmic reticulum stress, and autophagy

Binding affinity and dose-response characterization using receptor-assay methodologies