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By inhibiting Aurora-A, Aurora-B, and Aurora-C kinases, these compounds induce defects in mitotic spindle assembly, causing temporary cell cycle arrest and disrupting proper chromosome alignment during mitosis [78]

You're more likely to have vitamin B12 deficiency if you have a medical condition where your body can't absorb B12 or you follow a strict vegan diet

They discovered that treatment with BV at ST-36 inhibited Fos transcription in the superficial layer of the lumbar spinal cord, resulting in reduced paw edema and nociceptive behaviors on the injected side (Li et al., 2010)

Too high of a dose, you're not getting enough electrolytes, you're not getting enough micronutrients, macronutrients, you know, your blood sugar, sugar is low