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Contrary to the pathogenic effects previously mentioned, one study suggested that STING might be a negative regulator in the CIA model by modulating B cell functions ( + cells, CD4 + cells, and IL-6 ( 5 cGAS-STING signaling: a target for RA treatment According to the above description, cGAS-STING signaling primarily plays a pathogenic role in RA

in animal studies, the peptide has a positive effect on aged mice, demonstrating significant increases in their activity and health, as well as some positive visual changes in their fur

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PMID: 176 HarrisonSABedossaPGuyCDSchattenbergJMLoombaRTaubRet al